Molecular risk prediction in ANCA-associated crescentic glomerulonephritis: added value over clinical and histological parameters.
Our lab has developed expertise with the use of cutting-edge gene expression technologies in transplant pathology. We have recently started exploring the utility of these technologies in glomerular diseases, with preliminary evidence suggesting that biopsy-based gene expression provides added prognostic value in ANCA-associated crescentic glomerulonephritis compared with clinical and histological features alone. We are currently in the process of validating our initial discovery cohort findings (based on >400 native kidney biopsies from the University of Alberta) in an independent cohort of ~100 biopsies from the University of British Columbia.
About the Speaker:
Benjamin A. Adam, MD, FRCPC
Anatomical Pathologist, University of Alberta Hospital
Assistant Professor, Department of Laboratory Medicine and Pathology, University of AlbertaMedical Director, North Sector Clinical Trials Laboratory, Alberta Public Laboratories
Dr. Adam completed medical school and residency training in Anatomical Pathology at the University of Alberta, followed by subspecialty training in Renal Pathology at Harvard Medical School/Massachusetts General Hospital, Thoracic Pathology at Toronto General Hospital, and Transplantation Pathology at the University of Pittsburgh Medical Center. His research is focused on molecular renal and transplantation pathology, including the use of cutting-edge gene expression technologies to better diagnose and predict outcomes in various pre- and post-transplant diseases. The ultimate goal of this research is to develop more precise tools to facilitate the delivery of personalized medicine. He has authored over 20 peer-reviewed journal articles and traveled throughout the world to present and lecture on the topics of his research.
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Meeting ID: 422-122-779
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About the Seminars:
This new webinar series brings together two successful organizations with a common goal of improving and disseminating the knowledge of glomerular kidney diseases. The Renal Pathology Society promotes excellence in diagnosis and research and encourages training and education in renal disease to its members around the world. This series’ curriculum focuses on research in renal pathology and new technologies applied to renal pathology, including image analytics, machine learning, multi-‘omics, and computational pathology approaches to renal biopsy analyses. Through this collaboration with GlomCon, the RPS is committed to promoting excellence in the diagnosis of glomerular disease and to bringing the breakthrough innovations in this field to the GlomCon community, which as of May 2019 represents more than 2200 clinicians and pathologists from 108 countries.